Hydroxychloroquine alert . The Medicines Agency (ANSM) warned on Monday that the treatments tested against Covid-19 could cause serious adverse effects and should “in no case” be used for self-medication, while three deaths potentially linked to these treatments have been reported.
“Thirty” of serious adverse effects, including “three deaths” have so far been reported in patients with coronavirus treated with Plaquenil (hydroxychloroquine) but also other drugs such as Kaletra (an antiretroviral combining lopinavir / ritonavir), said Dominique Martin, the director general of the ANSM.
The problem is that we do not have a solid randomly controlled clinical trial yet.
There is a small negative trial. There is a small positive trial.
This is not sufficient. It is more wishful thinking than evidence-based medicine. Clinicians do not (yet) IMHO have enough hard evidence to consider early treatment with HCQ of patients suspected of COVID-19.
On the other hand:
http://www.leparisien.fr/amp/societe/covid-19-l-ansm-alerte-sur-les-effets-secondaires-graves-des-traitements-apres-3-deces-30-03-2020-8291049.php
The problem is that we do not have a solid randomly controlled clinical trial yet.
There is a small negative trial. There is a small positive trial.
This is not sufficient. It is more wishful thinking than evidence-based medicine. Clinicians do not (yet) IMHO have enough hard evidence to consider early treatment with HCQ of patients suspected of COVID-19.